Comprehensive review on flavonoids biological activities of Erythrina plant species

Erythrina species (Fabaceae) or coral trees are widely distributed in tropical and subtropical regions worldwide. They are used in traditional medicine for the treatment of various ailments, such as anxiety, inflammation, wound healing, and microbial infections. Alkaloids and flavonoids are the main bioactive constituents isolated from genus Erythrina. The present review sheds light on Erythrina species flavonoidal content, that can serve as lead compounds in managing various diseases, including oxidative stress, inflammation, diabetes, and cancer. It is a comprehensive study of the flavonoidal constituents from Erythrina species, with their structural diversity and reported biological activity. More than 370 flavonoid compounds were isolated from genus Erythrina, including flavones, flavonols, flavanones, chalcones, isoflavans, isoflav-3-enes, neoflav-3-ene, isoflavanones, isoflavones, pterocarpans, coumestans, arylcoumarins, coumaronochromones, arylbenzofurans, and biflavonoids.