Myocardial hypersensitivity to ischemic injury is not reversed by clonidine or propranolol in a predator-based rat model of posttraumatic stress disorder

- The psychosocial stress model of PTSD causes myocardial hypersensitivity to ischemic injury.
- Clonidine blocks anxiety-like behavior but not myocardial hypersensitivity to ischemia.
- Propranolol does not block anxiety or hypersensitivity to ischemia in this animal model of PTSD.