Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk

Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 28, Issue 21, 15 November 2018, Pages 3419-3424

Richard Caldwell, Lesley Liu-Bujalski, Hui Qiu, Igor Mochalkin, Reinaldo Jones, Constantin Neagu, Andreas Goutopoulos, Roland Grenningloh, Theresa Johnson, Brian Sherer, Anna Gardberg, Ariele Viacava Follis, Federica Morandi, Jared Head,