کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11263531 1678892 2019 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Glutamatergic facilitation of neural responses in MT enhances motion perception in humans
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
Glutamatergic facilitation of neural responses in MT enhances motion perception in humans
چکیده انگلیسی
There is large individual variability in human neural responses and perceptual abilities. The factors that give rise to these individual differences, however, remain largely unknown. To examine these factors, we measured fMRI responses to moving gratings in the motion-selective region MT, and perceptual duration thresholds for motion direction discrimination. Further, we acquired MR spectroscopy data, which allowed us to quantify an index of neurotransmitter levels in the region of area MT. These three measurements were conducted in separate experimental sessions within the same group of male and female subjects. We show that stronger Glx (glutamate + glutamine) signals in the MT region are associated with both higher fMRI responses and superior psychophysical task performance. Our results suggest that greater baseline levels of glutamate within MT facilitate motion perception by increasing neural responses in this region.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 184, 1 January 2019, Pages 925-931
نویسندگان
, , , , , , ,