کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1162778 1490900 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Simultaneous extraction and determination of albendazole and triclabendazole by a novel syringe to syringe dispersive liquid phase microextraction-solidified floating organic drop combined with high performance liquid chromatography
ترجمه فارسی عنوان
استخراج همزمان و تعیین آلبندازول و تری کلابندازول با استفاده از یک قطره آلی شناور منجمد ـ میکرواستخراج فاز مایع پراکنده سرنگ به سرنگ ترکیب شده با کروماتوگرافی مایع با کارایی بالا
کلمات کلیدی
قطره آلی شناور منجمد ـ میکرواستخراج فاز مایع پراکنده سرنگ به سرنگ؛ کروماتوگرافی مایع با کارایی بالا؛ آلبندزول؛ تری کلابندازول
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی


• A novel dispersive liquid phase microextraction was developed for ALB and TCB.
• The analytes are extracted in a closed system using of two connected syringes.
• The dispersion is done by injection & back injection of mixture of solvent/sample.
• The dispersion is done without the use of dispersing agent, ultrasonic bath or vortex mixer.
• The combination of method with HPLC-FLD allows trace determination of ALB and TCB.

A syringe to syringe dispersive liquid phase microextraction-solidified floating organic drop was introduced and used for the simultaneous extraction of trace amounts of albendazole and triclabendazole from different matrices. The extracted analytes were determined by high performance liquid chromatography along with fluorescence detection. The analytical parameters affecting the microextraction efficiency including the nature and volume of the extraction solvent, sample volume, sample pH, ionic strength and the cycles of extraction were optimized. The calibration curves were linear in the range of 0.1–30.0 μg L−1 and 0.2–30.0 μg L−1 with determination coefficients of 0.9999 and 0.9998 for albendazole and triclabendazole respectively. The detection limits defined as three folds of the signal to noise ratio were found to be 0.02 μg L−1 for albendazole and 0.06 μg L−1 for triclabendazole. The inter-day and intra-day precision (RSD%) for both analytes at three concentration levels (0.5, 2.0 and 10.0 μg L−1) were in the range of 6.3–10.1% and 5.0–7.5% respectively. The developed method was successfully applied to determine albendazole and triclabendazole in water, cow milk, honey, and urine samples.

Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 932, 17 August 2016, Pages 22–28
نویسندگان
, , ,