کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1253979 971320 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sesquiterpenes from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activity
ترجمه فارسی عنوان
Sesquiterpenes از برگ های تنباکوی نیکوتین و فعالیت ویروس موزائیکی ضدتنباکوی آنها
کلمات کلیدی
Sesquiterpenes؛ فعالیت ویروس موزائیکی ضدتنباکو (Anti-TMV)؛ تنباکوی نیکوتین ؛ توضیح ساختاری؛ Ningnanmycin
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
چکیده انگلیسی

In searching for more bioactive compounds, phytochemical investigations on the acetone extract of the leaves of Nicotiana tabacum resulted in the isolation of two new sesquiterpenes, nicosesquiterpene A and B (1 and 2), along with four known sesquiterpene derivatives (3–6). Structural elucidation of 1 and 2 was performed by spectral methods, such as HRMS, IR, UV, 1D and 2D NMR spectroscopy. Compounds 1 and 2 are the first naturally occurring pterosin-type sesquiterpene bearing an isopropyl moiety. Compounds 1–6 were also evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 exhibited high anti-TMV activity with inhibition rates of 36.7% and 45.6%, respectively, which is higher than that of positive control. The other compounds also showed potential activity with inhibition rates in the range of 22.7%–29.2%.

Two new sesquiterpenes (1 and 2) were isolated from the leaves of Nicotiana tabacum and exhibited high anti-TMV activities with inhibition rates of 36.7% and 45.6%, respectively.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Chemical Letters - Volume 27, Issue 5, May 2016, Pages 753–756
نویسندگان
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