A fluorous ethylenediamine promoted direct CH arylation of unactivated arenes with aryl halides

• A novel and recyclable fluorous ethylenediamine was prepared.
• The organocatalyst could promote the coupling without the aid of transition metal.
• A chain homolytic aromatic substitution mechanism was proposed.

A novel and recyclable fluorous ethylenediamine was prepared. Together with potassium tert-butoxide, the fluorous ethylenediamine showed a good activity in promoting the coupling of aryl halides with benzene derivatives without the aid of transition-metal catalysts. Furthermore, a chain homolytic aromatic substitution mechanism was proposed in this paper.

A novel and recyclable fluorous ethylenediamine was prepared. Together with potassium tert-butoxide, the fluorous ethylenediamine showed a good activity in promoting the coupling of aryl halides with benzene derivatives without the aid of transition-metal catalysts.Figure optionsDownload as PowerPoint slide