کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1345135 | 980181 | 2016 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Polystyrene supported benzoylthiourea—pyrrolidine organocatalyst for the enantioselective Michael addition
ترجمه فارسی عنوان
پلی استایرن از ترکیب بنزوئیلتوریورا پیرولیدین برای افزودن مایعات اضافی
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
چکیده انگلیسی
Herein the preparation of a swellable pearl-like copolymer of styrene with anchored (S)-1-benzoyl-3-(pyrrolidine-2-ylmethyl)thiourea (20–600 μm) and its application as a recyclable organocatalyst for the Michael addition of ketones to functionalized β-nitrostyrenes is described. The rate of the reaction taking place in the matrix of the swellable polymeric catalyst was comparable with the reaction rate in homogeneous medium. The corresponding functionalized 4-nitroketones were formed quantitatively with the enantiomeric excesses up to 98% ee. After a fivefold recycling of the catalyst, no decrease in the yield was detected, but the enantioselectivity was slightly lowered (95 → 88% ee).
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron: Asymmetry - Volume 27, Issue 16, 1 September 2016, Pages 782–787
Journal: Tetrahedron: Asymmetry - Volume 27, Issue 16, 1 September 2016, Pages 782–787
نویسندگان
Ladislav Androvič, Pavel Drabina, Markéta Svobodová, Miloš Sedlák,