کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1415670 985933 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Vertically aligned multiwall-carbon nanotubes to preferentially entrap highly metastatic cancerous cells
ترجمه فارسی عنوان
نانولوله های چندجداره کربن تراز شده عمودی برای به دام انداختن ترجیحی سلولهای سرطانی متاستاتیک بالا
موضوعات مرتبط
مهندسی و علوم پایه مهندسی انرژی انرژی (عمومی)
چکیده انگلیسی

We have investigated the entrapment of colon cancer cells with two different metastatic grades on arrays of multiwall carbon nanotubes. It has been observed that the fraction of entrapment of higher metastatic cancer cells is significantly more than lower metastatic grades. The observed effects are due to the more deformability and softness of higher metastatic malignant cells in comparison with the lower ones both for live and fixed cells. Also cell fixation results in a decrease of their entrapment due to an increase in cell rigidity by the fixation process. The present phenomenon describes a new application of vertically aligned carbon nanotubes to distinguish the healthy and cancerous cells by means of their different deformability properties during entrapment on such arrays.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbon - Volume 50, Issue 5, April 2012, Pages 2010–2017
نویسندگان
, , , , , ,