کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1642796 1517245 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecularly imprinted polyurethane grafted calcium alginate hydrogel with specific recognition for proteins
ترجمه فارسی عنوان
هیدروژل آلژینات کلسیم مورد استفاده در پلی یورتان را با استفاده از پروتئین شناخته شده مشخص می کند
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد فناوری نانو (نانو تکنولوژی)
چکیده انگلیسی


• Protein imprinting polyurethane grafted calcium alginate was synthesized.
• The imprinting efficiency varies with the increasing of grafting ratio.
• The adsorption isotherm of the hydrogels can be fitted with Freundlich model.
• The selective factor of imprinted hydrogel increases after modification.

Polyurethane grafted calcium alginate hydrogel microspheres intended for bovine serum albumin imprinting were prepared and characterized. The grafting modification was performed prior to the assembling of protein template with hydrogel, which was advantageous to maintain protein conformation and construct more accessible imprinted sites. It was found that the imprinted hydrogel had higher affinity to template molecules after modification. Investigations of grafting ratio influence on specific rebinding and competitive properties indicated that grafted side chains were beneficial to the selective recognition of protein.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Letters - Volume 143, 15 March 2015, Pages 248–251
نویسندگان
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