کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1993127 1064617 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Current anti-diabetes mechanisms and clinical trials using Morus alba L.
ترجمه فارسی عنوان
مکانیسم ضددیابت کنونی و آزمایش های بالینی با استفاده از توت سفید L.
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
چکیده انگلیسی


• Mulberry leaves possess the anti-diabetic effect since ancient times.
• The mechanisms of anti-diabetes are revolved in several molecular pathways in the meantime.
• Crosstalk and “critical nodes” would possibly be helpful for the further research in anti-diabetes.

BackgroundsDiabetes mellitus, especially type 2 diabetes, with its fast-rising prevalence, has become a global epidemic. Mulberry (Morus alba L.) leaf has been known to have hypoglycemic effects since ancient times. In Asia mulberry leaf is used as tea to complement the treatment of diabetes mellitus. The methods by which mulberry leaf affects the body and its mechanism when combined with chemical agents have been studied extensively.ConclusionsWe summarize the possible mechanisms of the anti-diabetic effects of mulberry leaf based on extraction procedures, in vitro and in vivo experiments, and clinical trials. We also discuss the hypothesis that crosstalk and “critical nodes” may be useful for a deeper molecular understanding of the treatment and prevention of diabetes with mulberry leaf.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Traditional Chinese Medical Sciences - Volume 3, Issue 1, January 2016, Pages 3–8
نویسندگان
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