کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1994561 1064799 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Using PET H2O15 brain imaging to study the functional-anatomical correlates of non-human primate communication
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Using PET H2O15 brain imaging to study the functional-anatomical correlates of non-human primate communication
چکیده انگلیسی
In this article, we describe methods for using oxygen-15 water (H2O15) positron emission tomography (PET) to explore the functional neuroanatomy of cognition in awake, non-human primates. The discussion is based on a recent study designed to identify regions in the monkey brain associated with perceiving auditory stimuli, and species-specific calls, in particular [Gil-da-Costa et al., Proc. Natl. Acad. Sci. USA 101 (2004) 17516-17521]. Details are provided concerning critical aspects of the experimental paradigm, including pre-scanning habituation sessions to acclimate the animals to the PET scanner environment, and details of a pilot study to determine the auditory stimulus parameters necessary to produce robust activity in brain regions known to process auditory information (belt and parabelt regions of monkey auditory cortex). Methods for acquiring and analyzing PET data to identify significant regions of brain activity in single animals are also presented.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Methods - Volume 38, Issue 3, March 2006, Pages 221-226
نویسندگان
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