کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2034762 1543057 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Do viruses use vectors to penetrate mucus barriers?
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
پیش نمایش صفحه اول مقاله
Do viruses use vectors to penetrate mucus barriers?
چکیده انگلیسی

I propose a mechanism by which viruses successfully infect new individuals, despite being immotile particles with no ability for directed movement. Within cells, viral particle movements are directed by motors and elements of the cytoskeleton, but how viruses cross extracellular barriers, like mucus, remains a mystery. I propose that viruses cross these barriers by hitch-hiking on bacteria or sperm cells which can transport themselves across mucosal layers designed to protect the underlying cells from pathogen attack. An important implication of this hypothesis is that agents that block interactions between viruses and bacteria or sperm may be new tools for disease prevention.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioscience Hypotheses - Volume 2, Issue 6, 2009, Pages 359–362
نویسندگان
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