کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2042625 | 1073228 | 2016 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecular clocks
ترجمه فارسی عنوان
ساعت های مولکولی
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
چکیده انگلیسی
SummaryIn the 1960s, several groups of scientists, including Emile Zuckerkandl and Linus Pauling, had noted that proteins experience amino acid replacements at a surprisingly consistent rate across very different species. This presumed single, uniform rate of genetic evolution was subsequently described using the term ‘molecular clock’. Biologists quickly realised that such a universal pacemaker could be used as a yardstick for measuring the timescale of evolutionary divergences: estimating the rate of amino acid exchanges per unit of time and applying it to protein differences across a range of organisms would allow deduction of the divergence times of their respective lineages (Figure 1).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 26, Issue 10, 23 May 2016, Pages R399–R402
Journal: - Volume 26, Issue 10, 23 May 2016, Pages R399–R402
نویسندگان
Michael S.Y. Lee, Simon Y.W. Ho,