کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2072809 1544734 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Glutamate supply positively affects serum cholesterol concentrations without increases in total protein and urea around the onset of puberty in goats
ترجمه فارسی عنوان
تأمین گلوتامات در غلظت کلسترول سرم بدون افزایش کل پروتئین و اوره در دوران بلوغ در بزها تاثیر مثبت دارد
کلمات کلیدی
بز ها، مکمل گلوتامات، متابولیت های خون، کلسترول، بلوغ
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی

Different neurotransmitter and neuromodulatory systems regulate synthesis and secretion of GnRH. Whereas the endocrine and neural systems are activated in response to the metabolic status and the circulating levels of specific blood metabolites, glutamate receptors have been reported at hepatic level. This study evaluated the possible effect of glutamate supplementation upon changes in serum concentrations across time for total protein (TP), urea (UR) and cholesterol (CL) around the onset of puberty in goats. Prepuberal female goats (n = 18) were randomly assigned to: (1) excitatory amino acids group, GLUT, n = 10; 16.52 ± 1.04 kg live weight (LW), 3.4 ± 0.12 body condition score (BCS) receiving an i.v. infusion of 7 mg kg−1 LW of l-glutamate, and (2) Control group, CONT, n = 8; 16.1 ± 1.04 kg LW, 3.1 ± 0.12 BCS. General averages for LW (23.2 ± 0.72 kg), BCS (3.37 ± 0.10 units), serum TP (65.28 ± 2.46 mg dL−1), UR (23.42 ± 0.95 mg dL−1), CL (77.89 ± 1.10 mg dL−1) as well as the serum levels for TP and UR across time did not differ (P > 0.05) between treatments. However, while GLUT positively affected (P < 0.05) both the onset (207 ± 9 vs. 225 ± 12 d) and the percentage (70 vs. 25%) of females showing puberty, a treatment × time interaction effect (P < 0.05) was observed in the GLUT group, with increases in serum cholesterol, coincident with the onset of puberty. Therefore, in peripuberal glutamate supplemented goats, serum cholesterol profile could act as a metabolic modulator for the establishment of puberty, denoting also a potential role of glutamate as modulator of lipid metabolism.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Animal Reproduction Science - Volume 147, Issues 3–4, 30 June 2014, Pages 106–111
نویسندگان
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