کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2393192 1101249 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pathobiology of Tendon and Ligament Injuries
موضوعات مرتبط
علوم پزشکی و سلامت علوم و ابزار دامپزشکی دامپزشکی
پیش نمایش صفحه اول مقاله
Pathobiology of Tendon and Ligament Injuries
چکیده انگلیسی

Tendon and ligament injuries are common in athletic horses and can be difficult to treat successfully. Tendons and ligaments are characterized by sparse fibroblasts embedded in a complex structural hierarchy of collagen-rich extracellular matrix (ECM) organized along lines of tension. This precise organizational scheme imparts the necessary mechanical properties for tendons and ligaments to function under high loads. The etiology of tendon and ligament injuries remains the subject of numerous ongoing research projects; however, acute overloading and accumulated microtrauma are the two predominant theories. Under normal physiologic loading, a balance is maintained between the degeneration of ECM and its repair by the resident fibroblast population. When damage occurs faster than it can be repaired, clinical signs of tendonitis or desmitis develop. The molecular and cellular responses that occur during tendon and ligament healing are important to understand, as they provide key points of control that may be targeted for new therapies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Techniques in Equine Practice - Volume 6, Issue 3, September 2007, Pages 168–173
نویسندگان
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