کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2647529 1139047 2015 7 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Late effects and quality of life after chemo-radiation for the treatment of anal cancer
ترجمه فارسی عنوان
اثرات بعدی و کیفیت زندگی پس از شیمی درمانی برای درمان سرطان مقعد
کلمات کلیدی
سرطان مقعد؛ شیمی تابش لگن ؛ اثرات بعدی؛ پیامدهای درمان
Anal cancer; Pelvic chemo-radiation; Late effects; Consequences of treatment
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی

PurposeThe aim of this study was to evaluate the late effects and quality of life of patients following chemo-radiation treatment for anal cancer.MethodsAll surviving anal cancer patients treated within NHS Lothian between 1990 and 2007 were invited to participate. Data were collected using the EORTC QLQ-C30, the EORTC QLQ-CR38 and the Memorial Sloan-Kettering Cancer Centre Bowel Function Instrument (MSKCC).ResultsOverall response rate was 46% (n = 42); mean age 54.7 years and with a median time interval of 63.8 months between treatment and completion of the questionnaires. Thirty-five percent of the participants were ‘rarely’ or ‘never’ able to wait 15 min to get to the toilet; 50% were ‘rarely’ or ‘never’ able to control the passage of gas; 35% limited the types of solid foods they eat; 22% had leakage of stool during the day; 39% required to use a protective pad and 29% altered their daily activities because of bowel function ‘always’ or ‘most of the time’. Seventeen percent of patients reported financial difficulties (‘quite a bit’ and ‘very much’). Both men and women reported high symptomology for sexual problems with a median score of 83.3 (50.0. 100.0).ConclusionThis study has shown that in a sub-set of patients treated with chemo-radiation for anal cancer, persistent treatment related issues are reported at a medium time interval of 5.3 years. Further work is now required to understand the impact of symptoms on day-to-day life and the challenges that people face in managing these inter-related and complex problems.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Oncology Nursing - Volume 19, Issue 5, October 2015, Pages 479–485
نویسندگان
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