کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2649631 1139272 2014 6 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Retrospective study of radiotherapy-induced skin reactions in breast cancer patients: Reduced incidence of moist desquamation with a hydroactive colloid gel versus dexpanthenol
ترجمه فارسی عنوان
مطالعه گذشته نگر واکنش های پوستی ناشی از پرتودرمانی در بیماران مبتلا به سرطان پستان: کاهش بروز پوسته شدن پوست با ژل کلوئیدی hydroactive در مقابل dexpanthenol
کلمات کلیدی
واکنش های پوستی ناشی از رادیوتراپی؛ درماتیت تابش؛ رادیوترامیت؛ سرطان پستان؛ پوسته شدن پوست؛ Dexpanthenol؛ ژل کلوئیدی Hydroactive؛ هیدروکلوئید؛ هیدروژل
Radiotherapy-induced skin reactions; Radiation dermatitis; Radiodermatitis; Breast cancer; Moist desquamation; Dexpanthenol; Hydroactive colloid gel; Hydrocolloid; Hydrogel
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی

PurposeDermatitis is a very frequent and distressing side effect of radiation therapy that may necessitate a treatment interruption when evolving towards more severe forms such as moist desquamation (MD). The aim of this study was to compare the efficacy of two topical agents, a dexpanthenol cream vs a hydroactive colloid gel combining absorbing and moisturising properties, in preventing MD in breast cancer patients.MethodsThis retrospective study compared two successive groups of breast cancer patients undergoing radiotherapy after breast-sparing surgery between 2008 and 2012. A group of 267 patients applied a 5% dexpanthenol cream on the irradiated zone throughout the course of their radiotherapy. Another group of 216 patients applied first the dexpanthenol cream then replaced it by the hydroactive colloid gel after 11–14 days of radiotherapy. Radiation treatment (total dose, technique, and equipment) was the same for the two groups. The clinical outcomes were the occurrence and time to onset of moist desquamation.Key resultsThe overall incidence of MD was significantly lower in patients who applied the hydroactive colloid gel (16%) than in those who applied the dexpanthenol cream (32%, odds-ratio = 0.35). Also, MD occurred significantly later with the hydroactive colloid gel than with the dexpanthenol cream (hazard ratio = 0.39).ConclusionsCompared with the dexpanthenol cream, the hydroactive colloid gel significantly reduced the risk of developing MD in patients undergoing radiotherapy for breast cancer. These promising results warrant further research on the efficacy of hydroactive colloid gels in managing radiation dermatitis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Oncology Nursing - Volume 18, Issue 5, October 2014, Pages 499–504
نویسندگان
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