کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2650311 1139367 2016 8 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
The relationship between cardiac hemodynamics and exercise tolerance in cystic fibrosis
ترجمه فارسی عنوان
رابطه بین همودینامیک قلب و تحمل ورزش در فیبروز کیستیک
کلمات کلیدی
برون ده قلبی؛ حجم ضربه؛ تست ورزش قلبی ریوی؛ ظرفیت ورزش؛ محدودیت عملکرد؛
Cardiac output; Stroke volume; CFTR; Cardiopulmonary exercise test; Exercise capacity; Functional limitation; Pulmonary functionBSA, body surface area; Ca2+, calcium; Ca-vO2, arterio-venous oxygen content difference; CF, cystic fibrosis; CFTR, cystic fibr
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

BackgroundIndividuals with cystic fibrosis (CF) have reduced pulmonary function and exercise tolerance. Additionally, these individuals may develop abnormal cardiac function. The implications of abnormal cardiac function on exercise tolerance are unclear in CF.ObjectiveStudy relationships between exercise cardiac hemodynamics and exercise tolerance in CF.Methods17 CF and 25 controls participated in cardiopulmonary exercise testing to measure exercise duration and peak workload (PW). Cardiac index (QI) was measured using acetylene rebreathe and oxygen uptake (VO2) breath-by-breath. Forced expiratory volume in 1-second (FEV1) was performed at rest.ResultsPeak QI was 6.7 ± 0.5 vs. 9.1 ± 0.3 mL/min/m2, CF vs. controls, respectively (P < 0.05). Linear regressions between QI (R2 = 0.63 and 0.51) and exercise duration or PW were stronger than VO2 (R2 = 0.35 and 0.37) or FEV1 (R2 = 0.34 and 0.36) in CF, respectively (P < 0.05).ConclusionThese data are clinically relevant suggesting attenuated cardiac function in addition to low airway function relate to exercise tolerance in CF.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Heart & Lung: The Journal of Acute and Critical Care - Volume 45, Issue 3, May–June 2016, Pages 283–290
نویسندگان
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