کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2680717 1142379 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Use of cardiovascular medicines in newly treated type 2 diabetes patients: A retrospective cohort study in general practice
ترجمه فارسی عنوان
استفاده از داروهای قلبی عروقی در بیماران دیابت نوع 2 تازه درمان شده: مطالعه همگروهی گذشته نگر در عمل کلی
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی


• Cardiovascular disease (CVD) agent use in newly treated type 2 diabetes was studied.
• Substantial CVD agent utilisation was noted.
• Younger aged subjects were less likely to receive guideline recommended therapies.
• It is possible that the use of statins and aspirin might be further optimised.

AimsTo describe the drug utilisation patterns of aspirin, antihypertensives, vasodilators, and statins in a cohort of newly treated type 2 diabetes subjects previously unexposed to CVD agents.MethodsA population-based retrospective cohort study was conducted using a national pharmacy claims database of newly treated type 2 diabetes subjects aged 40 years or older. Data on the use of aspirin, antihypertensives, vasodilators, and statins 1 year after antidiabetic agent initiation were analysed. Poisson regression with a robust error variance was used to estimate adjusted relative risk (RRadj) and 95% CIs between socio-demographic and treatment factors on CVD agent use.ResultsOver a 2-year period (2008–2009), 6093 subjects were identified. One year after antidiabetic agent initiation, 82% of the study population received at least one CVD agent, with 54% receiving aspirin, 64% receiving antihypertensives, 6% vasodilators, and 62% receiving statins. Subjects aged 40–49 years were significantly less likely than those aged 60–69 years to receive CVD agents (RRadj 0.83, 95% CI 0.80–0.87). Over 40% of subjects received antihypertensives without aspirin and statins, while 30% of subjects on statins did not receive aspirin.ConclusionsSubstantial CVD agent utilisation was noted 1 year after antidiabetic agent initiation. Being aged younger than 60–69 years was associated with decreased utilisation of CVD agents.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Primary Care Diabetes - Volume 10, Issue 4, August 2016, Pages 237–243
نویسندگان
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