کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2686735 1142978 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Changes in body weight during various types of chemotherapy in breast cancer patients
ترجمه فارسی عنوان
تغییرات در وزن بدن در طی انواع مختلف شیمی درمانی در بیماران مبتلا به سرطان پستان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مراقبت های ویژه و مراقبتهای ویژه پزشکی
چکیده انگلیسی

SummaryBackground & aimsWeight gain is a common problem for breast cancer patients treated with chemotherapy. It increases the risk of several comorbidities and possibly cancer recurrence. We assessed whether weight gain depends on the type of chemotherapy.MethodsIn a retrospective study among 739 breast cancer patients, we assessed whether change in body weight during chemotherapy differed between types of chemotherapy. Information about weight, clinical and personal factors was retrieved from medical records of breast cancer patients treated with chemotherapy between 2001 and 2010 in 4 different hospitals.ResultsBody weight information was complete in n = 483 patients (66%). There was substantial between-patients variability in weight change during chemotherapy: within the upper quintile of weight change, median weight gain was +6 kg, while in the bottom quintile median weight loss was of −3 kg. Adjusted multivariate regression analysis showed that change in weight differed between types of chemotherapy: women treated with anthracyclines + taxanes gained +0.9 kg (95%CI 0.1, 1.7) more than women treated with anthracyclines only. This differential change in weight was no longer statistically significant after taking into account that regimens with anthracyclines + taxanes have a longer duration than regimens with anthracyclines only.ConclusionThere was more weight gain among patients treated with anthracyclines + taxanes than among patients treated with anthracyclines-only. This is partly explained by the longer duration of regimes with anthracyclines + taxanes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: e-SPEN Journal - Volume 9, Issue 1, February 2014, Pages e39–e44
نویسندگان
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