کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2692902 1143483 2016 4 صفحه PDF ندارد دانلود کنید
عنوان انگلیسی مقاله
The effects of hormone replacement therapy on dry eye syndromes evaluated by Schirmer test depend on patient age
ترجمه فارسی عنوان
اثرات درمان جایگزینی هورمون بر سندرم های چشم خشک ارزیابی شده با استفاده از آزمون شرمر به سن بیمار بستگی دارد
کلمات کلیدی
درمان جایگزینی هورمون. یائسگی؛ سندرم چشم خشک؛ سن
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی چشم پزشکی
چکیده انگلیسی

PurposeThis study was performed to explore the effects of hormone replacement therapy (HRT) on aqueous tear production and tear quality in dry eye syndrome (DES) patients of different ages.MethodsEighty-eight women with DES at least one year after spontaneous menopause were randomly divided into the HRT group that were treated with orally estrogen and medroxyprogesterone acetate or a control group that did not receive any treatment. The aqueous tear production and tear quality were measured by Schirmer test and tear film break up time (TBUT) before and after one month of treatment. The subjects were subdivided according to age; the HRT group was divided into groups A (age range: 44–49 years) and B (age range: 50–57 years), and the controls were divided into groups C (age range: 46–49 years) and D (age range: 50–55 years). The changes in results of Schirmer test and TBUT before and after treatment were compared within each group and were correlated with the age of the participants.ResultsAfter one-month follow-up, HRT use improved the Schirmer test but the effect was significant only for participants less than 50 years old. The improvement in Schirmer test result was negatively correlated with the age of the participants. The TBUT did not change significantly within each group after HRT use.ConclusionsHRT use may improve aqueous tear production but not the quality of tears in DES, and the effect on tear production is dependent on age.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Contact Lens and Anterior Eye - Volume 39, Issue 2, April 2016, Pages 124–127
نویسندگان
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