کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2703786 1144648 2016 4 صفحه PDF ندارد دانلود کنید
عنوان انگلیسی مقاله
High frequency of squamous intraepithelial neoplasia in pterygium related to low ultraviolet light exposure
ترجمه فارسی عنوان
فراوانی بالای نئوپلازی داخل اسکواموس در ناخنک مربوط به قرار گرفتن در معرض نور کم ماوراء بنفش
کلمات کلیدی
PT، ناخنک؛ UV، اشعه ماوراء بنفش؛ OSSN، سطح چشم neoplasiaPterygium اسکواموس؛ نئوپلازی اسکواموس؛ نور فرابنفش
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی چشم پزشکی
چکیده انگلیسی

PurposeThe aim of this study was to determine the frequency of clinically unsuspected ocular surface squamous neoplasia (OSSN) in cases of biopsied pterygium (PT).MethodsWe reviewed 15,016 cases presented at the Henry C. Witelson Ocular Pathology Laboratory during the period 1993–2013. All cases with a clinical diagnosis of PT were included. Histopathological diagnoses were reviewed and demographic data were retrieved from histopathological request forms. All cases associated with OSSN were re-evaluated independently by two ocular pathologists. The classification of OSSN in PT cases was made based on the Armed Forces Institute of Pathology (AFIP) recommendations.ResultsTwo hundred and fifteen cases were diagnosed clinically as PT (1.43%) and 54% were from male patients. The average age at diagnosis was 53.4 ± 15.5 years. OSSN was identified in five cases (2.33%), and four of these cases were from female patients (80%). The average age of patients with PT and OSSN was similar to PT patients without OSSN (P > 0.05). Cases with OSSN were diagnosed as conjunctival intraepithelial neoplasia (CIN) I (60%), CIN II (20%), and CIN III (20%). There was complete agreement between the two pathologists (100%).ConclusionsThe relatively high rate of dysplasia in a low ultraviolet light index area challenges the main cause of this disease in our population, a hypothesis that should be evaluated in future studies. We suggest that all PT samples should be sent for histopathological evaluation even in areas with low ultraviolet light index.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Saudi Journal of Ophthalmology - Volume 30, Issue 2, April–June 2016, Pages 113–116
نویسندگان
, , , , , , , ,