کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2797365 | 1155649 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Men with hyperferritinemia and diabetes in the Mediterranean area do not have a higher iron overload than those without diabetes
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
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چکیده انگلیسی
AimTo assess the role of iron overload in type 2 diabetic men with hyperferritinemia.Methods150 men were recruited from a genetic screening programme for hereditary hemocromatosis (HH) and were tested for type 2 diabetes, other components of the metabolic syndrome, beta cell function (BCF), insulin sensitivity, high-sensitivity C-reactive protein and iron overload.ResultsFifty-one men had type 2 diabetes. They were older (p = 0.017) and 99 had lower BCF (p < 0.001) than non-diabetic men. None of the iron overload indexes was associated with diabetes.ConclusionsOur findings dispute a role of iron overload in the pathogenesis of type 2 diabetes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 91, Issue 2, February 2011, Pages e33–e36
Journal: Diabetes Research and Clinical Practice - Volume 91, Issue 2, February 2011, Pages e33–e36
نویسندگان
Núria Freixenet, Carme Vilardell, Gemma Llauradó, Olga Giménez-Palop, Eugenio Berlanga, Cristina Gutiérrez, Assumpta Caixàs, Joan Vendrell, José Miguel González-Clemente,