کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2798146 1155680 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cataract and type 1 diabetes mellitus
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Cataract and type 1 diabetes mellitus
چکیده انگلیسی

AimsTo evaluate the prevalence of cataract and the possible factors associated with cataract in young type 1 diabetes mellitus (DM).Methods293 patients were evaluated. The association of cataract with diabetic retinopathy (DR), retinal laser treatment, hypertension, body mass index, peripheral neuropathy, lipid profile, glycemic control, serum creatinine and albuminuria was evaluated.ResultsCataract was present in 19.8% (n = 58) of the sample. Patients with cataracts were older, had a higher frequency of history of retina photocoagulation treatment, higher serum creatinine values and higher prevalence of arterial hypertension. There was a progressive increase in cataract frequency according to the number of risk factors, starting to rise with two or more. In logistic regression model cataract was associated with mild/moderate DR (odd ratio (OR) 4.28 95% CI 1.63–11.29), severe DR (OR 4.07 95% CI 1.63–10.23) and macroalbuminuria (OR 2.34 95% CI 1.06–5.16).ConclusionThese data indicate a high prevalence of cataract in subjects with type 1 DM attending a general hospital in Southern Brazil and suggest that the more severe the disease process the greater is the risk of having this diabetic complication. Cataract should be suspected in young patients with two or more risk factors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 82, Issue 3, December 2008, Pages 324–328
نویسندگان
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