کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2909776 1405355 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Association between serum uric acid (SUA) levels and metabolic syndrome (MetS) components in personnel of Shahroud University of Medical Sciences
ترجمه فارسی عنوان
ارتباط بین سطوح اسید اوریک سرم (SUA) و مولفه های سندرم متابولیک (MetS) در پرسنل دانشگاه علوم پزشکی شاهرود
کلمات کلیدی
سندرم متابولیک؛ اسید اوریک سرم؛ IranMetS، سندرم متابولیک؛ SUA، اسید اوریک سرم؛ BMI، شاخص توده بدنی؛ WC، دور کمر؛ SBP، فشار خون سیستولیک؛ DBP، فشار خون دیاستولیک؛ کلسترول HDL، کلسترول لیپوپروتئین با چگالی بالا؛ TG
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

AimsSerum uric acid level has been suggested to be associated with metabolic syndrome risk factors. However, the association between metabolic syndrome and serum uric acid is still controversial and challenging. This study was aimed to investigate the association between serum uric acid levels and metabolic syndrome components in personnel of the Shahroud University of Medical Sciences.Material and methodsThis case–control study was conducted on 499 personnel aged 30–60 years old who were working in Shahroud University of Medical Sciences, in 2015. MetS was defined according to the National Cholesterol Education Program (NCEP) criteria. The relationship between serum UA level and the number of metabolic components was determined by linear regression analysis.ResultIn this study, the mean concentration of serum uric acid in men with the syndrome was higher than that in women. Mean serum UA level increased as the number of metabolic factors increased. The mean serum uric acid levels was 4.98 ± 1.64 in patients with metabolic syndrome and 4.5 ± 1.28 in non-patients (p = 0.005). Subject with abnormal uric acid were almost 2.62 times more likely than other subject to develop the syndrome.ConclusionsThe results of this study showed that only hypertriglyceridemia is a component which increases the risk of hyperuricemia. In addition, hyperuricemia increases the risk of metabolic syndrome by more than two fold. It seems that high uric acid can be considered as a predisposing factor for metabolic syndrome; thus, it is recommended to measure serum uric acid in routine tests.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes & Metabolic Syndrome: Clinical Research & Reviews - Volume 10, Issue 3, July–September 2016, Pages 132–136
نویسندگان
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