کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2925974 1575785 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Gender differences in the prognostic impact of chronic kidney disease in patients with left ventricular systolic dysfunction following ST elevation myocardial infarction treated with primary percutaneous coronary intervention
ترجمه فارسی عنوان
تفاوت های جنسیتی در اثر پیش آگهی بیماری مزمن کلیه در بیماران با اختلال سیستولیک بطن چپ به دنبال انفارکتوس میوکارد درمان شده با مداخله کرونری از راه پوست اصلی
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

Background/AimRenal function potentially has different prognostic impact in men and women with acute myocardial infarction. The aim of this study was to evaluate the prognostic impact of chronic kidney disease (CKD) on five-year all-cause mortality in men and women with left ventricular systolic dysfunction (LVSD) following ST elevation myocardial infarction (STEMI).MethodWe included 348 consecutive STEMI patients who were treated with primary percutaneous coronary intervention (pPCI) and had a left ventricular ejection fraction < 40%. CKD was defined as baseline creatinine clearance (CrCl) < 60 ml/min. Patients with cardiogenic shock at admission were excluded.ResultsAmong analyzed patients, 104 patients (29.8%) were women, and 244 patients (70.1%) were men. Compared with male patients, female patients were older. Females were more likely to have previous angina and hypertension. CKD was more common in women compared with men (54.8% vs. 22.5%, p<0.001). Female gender and older age were independent predictors of CKD. No significant difference in five-year all-cause mortality was between men and women (27.8% vs. 23.3%, p=0.370). In a Cox regression model (adjustments were made for age, Killip class at admission, post-procedural flow TIMI<3, left main stenosis and women with diabetes), CKD remained an independent predictor of five-year all-cause mortality in men (HR 2.2; 95% CI 1.22–3.3, p=0.007).ConclusionsAlthough pre-terminal CKD was more frequently noted in women, it was an independent predictor of five-year mortality exclusively in men. Different prognostic significance of CKD between sexes indicates that renal function must be considered in the prognosis of men and women following acute myocardial infarction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hellenic Journal of Cardiology - Volume 57, Issue 2, March–April 2016, Pages 109–115
نویسندگان
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