کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2928647 1576142 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Intracoronary injection of tirofiban prevents microcirculation dysfunction during delayed percutaneous coronary intervention in patients with acute myocardial infarction
ترجمه فارسی عنوان
تزریق Intracoronary از tirofiban مانع از اختلال میکروسیرکولاسیون در طول مداخله کرونری از راه پوست تاخیری در بیماران مبتلا به انفارکتوس حاد میوکارد می شود
کلمات کلیدی
شاخص مقاومت در برابر میکروسیرکولاسیون ؛ Tirofiban؛ مداخله کرونری از راه پوست تاخیری
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

ObjectiveTo determine whether tirofiban can prevent microcirculation dysfunction during delayed percutaneous coronary intervention (PCI) of spontaneously recanalized and severe narrowing coronary artery in patients with acute myocardial infarction.Methods62 patients who have a single angiographically confirmed narrowing culprit coronary artery for more than 75% between 7 and 14 days after the onset of acute myocardial infarction were randomly divided into the tirofiban group (32 cases) and the placebo group (30 cases). All the patients received measurement of the index of microcirculatory resistance (IMR) before tirofiban/placebo administration and PCI. After PCI, IMR value was measured again.ResultsThere was no significant variation between the two groups before PCI (11.67 ± 6.45 of placebo group vs. 14.65 ± 12.45 of tirofiban group, P = 0.158). After PCI, the IMR value of the tirofiban group is significantly lower than that of the placebo group (23.63 ± 9.91 of placebo group vs. 16.75 ± 9.98 of tirofiban group, P = 0.008).ConclusionsIntracoronary injection of tirofiban can significantly prevent the abnormal increase of IMR value during delayed PCI in patients with acute myocardial infarction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Cardiology - Volume 208, 1 April 2016, Pages 137–140
نویسندگان
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