کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2964199 1578147 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
In vitro stem cell differentiation into cardiomyocytes: Part 1. Culture medium and growth factors
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
In vitro stem cell differentiation into cardiomyocytes: Part 1. Culture medium and growth factors
چکیده انگلیسی

SummaryRecent developments in the field of regenerative stem cell therapy for ischaemic heart disease have lead to an explosion in the clinical trial realm. At present no consensus exists regarding, amongst others, the optimal cell type as well as the underlying mechanism of action for any clinical improvement observed. As de novo reconstitution of myocardial tissue from multipotent stem cells is one of the working theories, the transdifferentiation potential of cellular populations under investigation into cardiomyocyte lineage phenotypes must ideally be assessed in preclinical bench work. Culture medium composition and a variety of growth factors are crucial determinants in this process. We discuss all relevant data acquired from in vitro work.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiothoracic-Renal Research - Volume 1, Issue 2, September 2006, Pages 107–114
نویسندگان
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