کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
323022 540464 2016 6 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
Social and physical environments as a source of individual variation in the rewarding effects of testosterone in male California mice (Peromyscus californicus)
ترجمه فارسی عنوان
محیط اجتماعی و فیزیکی به عنوان یک منبع از تنوع منحصر به فرد در اثرات پاداش تستوسترون در موش های نر کالیفرنیا
کلمات کلیدی
تستوسترون؛ تقویت کننده اثرات؛ قلمرو؛ مطبوع ترجیح مکان؛ اتصال جفت
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی


• There is plasticity in the rewarding effects of testosterone (T).
• Pair-bonding experience coupled with residency enhances T-induced conditioned place preferences (CPPs).
• Social isolation enhances T-induced CPPs to unfamiliar environments.
• In males housed with siblings, T-induced CPPs are prevented.

Despite extensive research revealing the occurrence of testosterone (T) pulses following social encounters, it is unclear how they lead to varied behavioral responses. We investigated the influence of residency (home versus unfamiliar environment) and social/sexual experience (pair-bonded, isolated or housed with siblings) on the plasticity of T's rewarding effects by measuring the development of conditioned place preferences (CPPs), a classical paradigm used to measure the rewarding properties of drugs. For pair-bonded males, T-induced CPPs were only produced in the environment wherein the social/sexual experience was accrued and residency status had been achieved. For isolated males, the T-induced CPPs only occurred when the environment was unfamiliar. For males housed with a male sibling, the T-induced CPPs were prevented in both the home and unfamiliar chambers. Our results reveal the plasticity of T's rewarding effects, and suggest that the behavioral functions of T-pulses can vary based on social/sexual experience and the environment in which residency was established. The formation of CPPs or reward-like properties of drugs and natural compounds can therefore exhibit malleability based on past experience and the current environment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hormones and Behavior - Volume 85, September 2016, Pages 30–35
نویسندگان
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