کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
3276098 1208528 2016 5 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله
Effect of soy protein isolate preload on postprandial glycemic control in healthy humans
ترجمه فارسی عنوان
اثر پیش بارگذاری ایزوله پروتئین سویا بر کنترل قند خون پس از صرف غذا در انسان سالم
کلمات کلیدی
گلوکز؛ انسولین؛ ایزوله پروتئین سویا؛ آزمون تحمل گلوکز خوراکی؛ پاسخ دز
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی


• Soy protein isolate consumption before oral glucose tolerance test (as a simulated carbohydrate-rich main meal) improves postprandial glycemia.
• Soy protein isolate preload enhanced the insulinotropic effect in a dose-dependent manner.
• This positive effect could be induced by not only stimulating insulin secretion but also by possibly slowing gastric emptying.

ObjectivePremeal consumption of whey protein improves the postmeal glycemic profile, but little information exists on soy protein. The study aim was to examine the effect of consuming different amounts of a soy protein isolate (SPI) before a 75-g oral glucose tolerance test (OGTT) on subsequent glycemic control.MethodsAfter overnight fasting, eight healthy young subjects consumed a 400-mL liquid meal containing 0 g (SP0), 20 g (SP20) or 40 g (SP40) SPI. Thirty minutes after SPI consumption, an OGTT was performed to evaluate the individual glycemic response. Blood glucose and plasma insulin concentrations were measured immediately before the SPI preload (i.e., 30 min before the start of the OGTT) and before (−10 min) and during the OGTT (15, 30, 45, 60, 90, and 120 min).ResultsThe incremental area under the curve and peak blood glucose response were significantly less for SP40 than those for SP0 and SP20. Insulin secretion was significantly higher for SP20 and SP40 than that for SP0 before and at 15 min after oral glucose consumption. The incremental area under the curve of plasma insulin was significantly higher for SP20 and SP40 than that for SP0.ConclusionsAn SPI preload of 40 g, but not 20 g, improved glycemic control in young healthy subjects. Glycemic control appears to be attributed not only to the exaggerated insulin response to SPI preload, but also to non-insulin dependent mechanism(s), such as delayed gastric emptying.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition - Volume 32, Issue 9, September 2016, Pages 965–969
نویسندگان
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