کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
33056 44954 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Improvement of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) production by dual feeding with levulinic acid and sodium propionate in Cupriavidus necator
ترجمه فارسی عنوان
بهبود تولید Poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) با تغذیه دوگانه با اسید لووولینیک و پروپیونات سدیم در Cupriavidus necator
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی


• Ping-Pong kinetic mechanism for the production of PHBV with 80% 3-HV content.
• Specific roles of levulinic acid and sodium propionate for PHBV production.
• Tuning of initial concentration of substrates for overall process improvement.
• Production of PHBV with 80% 3-HV content with 3.9 mg/L/hour volumetric productivity.

In the context of increasing volatility of oil prices, replacement of petroleum based plastics by bioplastics is a topic of increasing interest. Poly(hydroxyalkanoate)s (PHAs) are among the most promising families in this field. Controlling composition of the polymer on the monomeric level remains a pivotal issue. This control is even more difficult to achieve when the polymer is not synthesized by chemists, but produced by nature, in this case, bacteria. In this study mechanism and role of two 3-hydroxyvalerate (3-HV) inducing substrates on the production of PHBV with high, 80%, 3-HV content were evaluated. It was found that levulinic acid contributes to biomass and bio-polymer content enhancement, whereas sodium propionate mainly contributes to 3-HV enhancement. Optimized proportions of feeding substrates at 1 g/L and 2.5 g/L, respectively for levulinic acid and sodium propionate allowed a 100% productivity enhancement, at 3.9 mg/L/hour, for the production of PHBV with 80% 3-HV.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: New Biotechnology - Volume 33, Issue 1, 25 January 2016, Pages 231–236
نویسندگان
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