کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
34178 45008 2016 6 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Probiotic properties of genetically engineered Lactobacillus plantarum producing porcine lactoferrin used as feed additive for piglets
ترجمه فارسی عنوان
خواص پروبیوتیک Lactobacillus plantarum تولید شده از ژنتیک تولید لاکتوفرین سوسیس به عنوان افزودنی خوراک برای خوک ها
کلمات کلیدی
لاکتوباسیلوس پلانتاروم؛ لاکتوفرین بز افزودنی های مواد؛ خواص پروبیوتیک
Lactobacillus plantarum; Porcine lactoferrin; Feed additive; Probiotic properties
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی


• The genetically engineered L. plantarum/pPG-pLF expressing porcine lactoferrin.
• Providing the L. plantarum/pPG-pLF for weaned piglets.
• L. plantarum/pPG-pLF would be as an alternative to antibiotics.

In this study, a genetically engineered Lactobacillus (L.) plantarum producing porcine lactoferrin (pLF) was developed and used as feed additive in the daily diet of weaned piglets were investigated, involving in growth performance, intestinal morphology and immunological indices. Results showed that the addition of L. plantarum/pPG-pLF in basal diet of weaned piglets significantly increased the average daily gain and feed intake, improved feed efficiency, and reduced incidence of diarrhea, compared to control group received basal diet only. The villus height in duodenum, ileum and jejunum, and the ratio of villus height to crypt depth of piglets fed with L. plantarum/pPG-pLF showed significantly increased levels. The number of Escherichia coli was decreased and the viable counts of Bifidobacterium and Lactobacillus were increased in intestine of piglets received L. plantarum/pPG-pLF than basal diet only or supplemented with Aureomycin. Moreover, immunological indices were determined that were induced by L. plantarum/pPG-pLF and results showed that the levels of total IgG, interleukin-2 and secretory immunoglobulin A were higher in experimented piglets than control group, while the level of interleukin-4 was reduced. The genetically engineered L. plantarum developed in this study provided a healthy and eco-friendly agent for weaned piglets against weaning stress and infections.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Process Biochemistry - Volume 51, Issue 6, June 2016, Pages 719–724
نویسندگان
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