کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3453447 1595915 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
An overview of the current methodologies used for evaluation of anti-fertility agents
ترجمه فارسی عنوان
یک مرور کلی از روش های فعلی مورد استفاده برای ارزیابی عوامل ضدبارداری
کلمات کلیدی
مدل های پیش بالینی؛ عوامل ضد باروری؛ مرور
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

Discoveries in the past two decades have continued to improve our understanding of the mechanism of fertilization and animal models have played a significant role to define the basic mechanism of anti-fertility agents. In vivo models have been developed in the past years to study the anti-fertility agents. Methods that are used in anti-fertility study can be categorized into method including estimation of sex hormones, assessment of sperm motility and count, assessment of sperm viability and morphology, mating trial test body, sex organ weights, abortifacient activity, post-coital anti-fertility activity, effect on estrous cycle, anti-estrogenic activity, anti-gonadotrophic effect and quantification of fructose in seminal vesicle, histopathology, and biochemical methods. This review aims to highlight some of the new and currently, used experimental models that are used for the evaluation of anti-fertility agents.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Pacific Journal of Reproduction - Volume 5, Issue 3, May 2016, Pages 175–178
نویسندگان
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