کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3942410 | 1410079 | 2016 | 4 صفحه PDF | دانلود رایگان |
• Race-Ethnicity is a risk factor for complete and partial molar pregnancy in the United States.
• Asian women are at increased risk of complete mole, and decreased risk of partial mole compared to whites
ObjectiveTo quantify the effect of race/ethnicity on risk of complete and partial molar pregnancy.MethodsWe conducted a cross-sectional study including women who were followed for complete or partial mole and those who had a live singleton birth in a teaching hospital in the northeastern United States between 2000 and 2013. We calculated race/ethnicity-specific risk of complete and partial mole per 10,000 live births, and used logistic regression to estimate crude and age-adjusted relative risks (RR) of complete and partial mole.ResultsWe identified 140 cases of complete mole, 115 cases of partial mole, and 105,942 live births. The risk of complete mole was 13 cases per 10,000 live births (95% confidence interval [CI] 11–16) and that of partial mole was 11 cases per 10,000 live births (95% CI 9–13). After age-adjustment, Asians were more likely to develop complete mole (RR 2.3 95% CI 1.4–3.8, p < 0.001) but less likely to develop partial mole (RR 0.2; 95% CI 0.04–0.7, p = 0.02) than whites. Blacks were significantly less likely than whites to develop partial mole (RR 0.4; 95% CI 0.2–0.8, p = 0.01) but only marginally less likely to develop complete mole (RR 0.6; 95% CI 0.3–1.0, p = 0.07). Hispanics were less likely than whites to develop complete mole (RR 0.4; 95% CI 0.2–0.7, p = 0.002) and partial mole (RR 0.4; 95% CI 0.2–0.9, p = 0.02).ConclusionRace/ethnicity is a significant risk factor for both complete and partial molar pregnancy in the northeastern United States.
Journal: Gynecologic Oncology - Volume 143, Issue 1, October 2016, Pages 73–76