کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4200924 1279382 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of anti-aphthous activity of decoction of Nicotiana tabacum leaves as a mouthwash: a placebo-controlled clinical study
ترجمه فارسی عنوان
بررسی فعالیت ضدآفت جوشانده برگ های گل توتون به عنوان دهانشویه: یک مطالعه بالینی کنترل شده با پلاسبو
کلمات کلیدی
دهان، آفت؛ توتون و تنباکو؛ درد، زخم؛ پزشکی، سنتی؛ درمان های مکمل. دهان شویه
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
چکیده انگلیسی

ObjectiveTo determine the effects of decoction derived from the leaves of Nicotiana tabacum (L.) as a mouthwash on minor recurrent aphthous.MethodsA randomized double-blinded placebo-controlled clinical trial was conducted on 60 patients with minor recurrent aphthous. Treatment comprised of application of tobacco or placebo mouthwash (10 mL 3 times a day) for 5 days. Clinical evaluation included pain level using a visual analog scale and ulcer size on days 1, 3, and 5 were measured. Adverse effects after mouthwash application were recorded, and the oral mucosa was examined by the investigator at each visit.ResultsA total of 54 subjects with the mean age (38 ± 10) years fulfilled the study. No minor and major adverse effects were observed. In the treatment group, ulcer pain score was decreased by 79.2% and 93.8% and ulcer size was reduced by 69.1% and 92.2% (days 3 and 5, respectively), which was significantly greater than the control group (P < 0.01).ConclusionThe decoction prepared with of Nicotiana tabacum leaves, used as mouthwash are well-tolerated and safe, and can be used for the management of recurrent aphthous.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Traditional Chinese Medicine - Volume 36, Issue 2, April 2016, Pages 160–164
نویسندگان
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