کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4476429 1315594 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Variability in antioxidant/detoxification enzymes of Sinonovacula constricta exposed to benzo[a]pyrene and phenanthrene
ترجمه فارسی عنوان
تنوع در آنزیم های آنتی اکسیدان/سم زدایی از Sinonovacula constricta در معرض benzo[a]pyrene و فنانترن
کلمات کلیدی
پاسخ آنتی اکسیدانی، نشانگر؛ benzo[a]pyrene . فنانترن (PHE)؛ constricta Sinonovacula
موضوعات مرتبط
مهندسی و علوم پایه علوم زمین و سیارات اقیانوس شناسی
چکیده انگلیسی


• Antioxidant biomarkers including EROD, GST, SOD, GSH, and AHH were used.
• The response of two PAH compounds of gill in clam was compared.
• Significant imbalances of oxidative status were induced by environmental pollutant B(a)P and PHE.
• The antioxidant parameters were used to determine potential toxic effects of B(a)P and PHE.

The purpose of this study was to investigate the toxic effects induced by benzo[a]pyrene and phenanthrene. For this purpose, a study was performed on the clam exposed to 0.0, 0.5, 4.5 μgL− 1 B(a)P and PHE for 15 days using parameters of antioxidant defenses and oxidative stress. Antioxidant biomarkers including ethoxyresorufin-O-deethylase, glutathione S-transferase, superoxide dismutase, and glutathione and rylhydrocarbon hydroxylasein gills of Sinonovacula constricta, were analyzed after a 1-, 3-, 9- and 15-day exposure to seawater containing B(a)P and PHE. Integrated biomarker response was calculated by combining multiple biomarkers into a single value. The results showed that the activity of all antioxidant biomarkers was induced throughout the exposure period, and different patterns of variations were detected with exposure time. In addition, the study showed that the two concentrations used caused the activation of different general detoxification mechanisms, and the same concentration at different two PAH compounds induced different toxicity responses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Marine Pollution Bulletin - Volume 109, Issue 1, 15 August 2016, Pages 507–511
نویسندگان
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