کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
49269 46730 2016 3 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Sc(OTf)3-catalyzed three-component cascade reaction: One-pot synthesis of substituted 3-oxoisoindoline-1-carbonitrile derivatives
ترجمه فارسی عنوان
کاتالیز واکنش cascade سه جزءSc(OTf)3 : سنتز یک دیگ از جایگزین مشتقات 3-oxoisoindoline-1-carbonitrile
کلمات کلیدی
Isoindolinones؛ واکنش Cascade را؛ آمین. SC (OTF) 3
Isoindolinones; Cascade reaction; Amines; Sc(OTf)3
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی کاتالیزور
چکیده انگلیسی


• A facile method for the synthesis of isoindolinones was developed.
• A broad scope of amine substrates was suitable for this process.
• Good to excellent yields (up to 97%) were achieved in most cases.

A facile and efficient approach for the synthesis of N-substituted 3-oxoisoindoline-1-carbonitrile derivatives has been developed, with a Sc(OTf)3-catalyzed three-component Strecker/Lactamization cascade reaction involving methyl 2-formylbenzoate, TMSCN and amines in ethanol at room temperature. Good to excellent yields for a broad scope of amine substrates were achieved.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Catalysis Communications - Volume 74, 10 January 2016, Pages 119–121
نویسندگان
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