Nanochitosan: A biopolymer catalytic system for the synthesis of 2-aminothiazoles

• Chitosan nanoparticles as an excellent biopolymer catalytic system in organic reaction
• Introducing nanochitosan for the synthesis of 2-aminothiazoles
• Generality of the catalyst, easiness of separation, and recycled several times

A convenient and efficient method is described for the synthesis of 2-aminothiazoles by one-pot reaction of ketone and thiourea using chitosan nanoparticles under mild condition. Nanochitosan was used as a biodegradable and green catalyst for this reaction in satisfactory yields. The attractive advantages of the present process include easy isolation of products, milder and cleaner conditions, higher purity and yields and easier work-up procedure.

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