|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|4957970||1445227||2018||14 صفحه PDF||سفارش دهید||دانلود کنید|
- We propose an integrated learning-based method to segment atherosclerotic carotid plaque in ultrasound image.
- Four different classification algorithms, along with the auto-context iterative model, are employed to implement the pixel-wise classification, respectively.
- The best results are obtained by the proposed method, integrating the random forest and auto-context model.
- Experimental results show that our method achieves the same performance as that by existed methods.
- Our proposed learning-based integrated framework could be helpful for the measurement of carotid plaque burden.
Background and objectiveCarotid artery atherosclerosis is an important cause of stroke. Ultrasound imaging has been widely used in the diagnosis of atherosclerosis. Therefore, segmenting atherosclerotic carotid plaque in ultrasound image is an important task. Accurate plaque segmentation is helpful for the measurement of carotid plaque burden. In this paper, we propose and evaluate a novel learning-based integrated framework for plaque segmentation.MethodsIn our study, four different classification algorithms, along with the auto-context iterative algorithm, were employed to effectively integrate features from ultrasound images and later also the iteratively estimated and refined probability maps together for pixel-wise classification. The four classification algorithms were support vector machine with linear kernel, support vector machine with radial basis function kernel, AdaBoost and random forest. The plaque segmentation was implemented in the generated probability map. The performance of the four different learning-based plaque segmentation methods was tested on 29 B-mode ultrasound images. The evaluation indices for our proposed methods were consisted of sensitivity, specificity, Dice similarity coefficient, overlap index, error of area, absolute error of area, point-to-point distance, and Hausdorff point-to-point distance, along with the area under the ROC curve.ResultsThe segmentation method integrated the random forest and an auto-context model obtained the best results (sensitivity 80.4â¯Â±â¯8.4%, specificity 96.5â¯Â±â¯2.0%, Dice similarity coefficient 81.0â¯Â±â¯4.1%, overlap index 68.3â¯Â±â¯5.8%, error of area -1.02â¯Â±â¯18.3%, absolute error of area 14.7â¯Â±â¯10.9%, point-to-point distance 0.34â¯Â±â¯0.10â¯mm, Hausdorff point-to-point distance 1.75â¯Â±â¯1.02â¯mm, and area under the ROC curve 0.897), which were almost the best, compared with that from the existed methods.ConclusionsOur proposed learning-based integrated framework investigated in this study could be useful for atherosclerotic carotid plaque segmentation, which will be helpful for the measurement of carotid plaque burden.
Journal: Computer Methods and Programs in Biomedicine - Volume 153, January 2018, Pages 19-32