|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5124241||1378441||2017||3 صفحه PDF||سفارش دهید||دانلود کنید|
SummaryObjectivesThis study aimed to identify the changes in dosing of botulinum toxin-A for adductor spasmodic dysphonia (ADSD) over a prolonged period.Study DesignThis is a retrospective chart review.MethodsOne hundred thirteen subjects treated for ADSD from 2003 to 2013 were identified from a clinical database. Subject age, gender, and total injection dose amount were all recorded for all subjects who had at least 10 injections.ResultsFifty-four subjects met criteria for inclusion. There were no age or gender differences in the starting dose for subjects. Dosing decreased significantly compared with the second dose (5.05âÂ±â1.623 Units), by the sixth dose (4.26âÂ±â1.698 Units), and continued through the 10th dose (4.08âÂ±â2.019 Units) (Pâ<â0.005 for all).ConclusionsBotulinum toxin-A dosing for ADSD decreases consistently over subsequent injections after the initial two dose titrations.
Journal: Journal of Voice - Volume 31, Issue 3, May 2017, Pages 363-365