کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5131353 1378743 2017 8 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله
High adhesion strength and hybrid irreversible/reversible full-PDMS microfluidic chips
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
High adhesion strength and hybrid irreversible/reversible full-PDMS microfluidic chips
چکیده انگلیسی


- SWB offers simple, fast, and low cost operation requiring only a laboratory oven.
- Microdevices herein described showed burst pressures of up to 4.5 MPa.
- Reversible behavior is crucial in stages of research and development.
- Chips obtained after successive detachment/bonding steps withstood high pressure.
- Emulsifications at high flow rates produced monodisperse dispersions.

To the best of our knowledge, this paper outlines for the first time high adhesion and hybrid irreversible/reversible microfluidic devices fully composed of polydimethylsiloxane (PDMS). These chips were fabricated by the sandwich bonding (SWB), a method that was recently deployed by our group. SWB offers simple, fast, and low cost operation requiring only a laboratory oven. The devices showed burst pressures of up to 4.5 MPa. This value is more than tenfold the pressures withstood by the full-PDMS chips described in literature. In terms of the reversible behavior, the ability for disassembling the chip slides is crucial in research and development stages, especially when the device integrates high-cost components or harsh cleaning steps are needed. Following successive steps of detachment and bonding, the channels still withstood high pressures of approximately 1.8 MPa. Finally, the emulsification of corn oil 4.0% w/w to polyglycerol polyricinoleate with 10.0 μmol L−1 rhodamine B aqueous solution was realized to show the relevance in enhancing the flow rate in microfluidics. Such experiment was conducted at total flow rates of 0.8-160.0 μL min−1. The decrease in size and polydispersity of the droplets was observed at increasing flow rates. Monodisperse emulsions were achieved only at 160.0 μL min−1.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 951, 25 January 2017, Pages 116-123
نویسندگان
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