کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5132092 | 1491478 | 2017 | 9 صفحه PDF | دانلود رایگان |
The compound, ethyl 5-(4-chlorophenyl)-3-methyl-1-phenyl-1H-pyrazole-4-carboxylate was synthesized by the reaction of ethyl 2-(4-chlorobenzylidene)-3-oxobutanoate and phenylhydrazine hydrochloride. The synthesized compound was characterized by 1H NMR and mass spectral analysis and finally the structure was confirmed by single crystal X-ray diffraction studies. The compound C19H17ClN2O2 crystallizes in the triclinic crystal system, in Ï1¯ space group. The structure exhibits intramolecular hydrogen bonds of the type CH...O and contributes to the structural stability. The molecular structure is also stabilized by the Ïâ¦Ï interactions. The antimicrobial activities of the compound have been studied for their pharmacological importance. Further, the Hirshfeld surface analysis reveals the nature of molecular interactions; the fingerprint plot provides information about the percentage contribution from each individual molecular contact to the surface.
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Journal: Chemical Data Collections - Volumes 9â10, August 2017, Pages 89-97