کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5137287 | 1494531 | 2017 | 8 صفحه PDF | دانلود رایگان |
- Antioxidant properties of LAB stains isolated from yak yogurt were investigated.
- Screened strain of L. delbrueckii F17 had high free radical scavenging activity.
- L. delbrueckii F17 exhibited excellent tolerance to simulated GI tract.
- L. delbrueckii F17 effectively alleviated the oxidative stress of ageing mice.
- The strain could be applied as a potential antioxidant strain in functional food.
This study investigated the antioxidant properties of lactic acid bacteria (LAB) isolated from spontaneously fermented yak milk collected on the Tibetan Plateau. Nine different species of LAB strains with high 2,2-diphenyl-1picrylhydrazyl radical-scavenging activity were screened from 403 isolates, and most of the selected LAB strains exhibited higher antioxidant activity than the reference strains from low-altitude areas. Among the 9 screened strains, L. delbrueckii subsp. bulgaricus F17 showed the greatest probiotic potential due to its high free radical scavenging activity (scavenging 59% OH and 54% O2â) and high survival rate (58%) within a simulated gastrointestinal tract. After administering the strain to ageing mice induced by d-galactose, the glutathione peroxidase activity in mouse livers and sera and the superoxide dismutase activities in mouse sera and brains increased significantly, while malondialdehyde levels in mouse livers and sera decreased significantly. This unique isolate could be considered a potential antioxidant strain for functional food production.
Journal: Journal of Functional Foods - Volume 35, August 2017, Pages 481-488