Asymmetric synthesis of optically active 3-amino-1,2-diols from N-acyl-protected allylamines via catalytic diboration with Rh[bis(oxazolinyl)phenyl] catalysts

Asymmetric diboration of N-acyl-protected allylamines such as substituted imides, amides, and carbamates catalyzed by chiral rhodium[bis(oxazolinyl)phenyl] complexes followed by oxidation in one-pot was realized to produce optically active 3-amino-1,2-propanediol derivatives in high enantioselectivities up to 99%.