کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5279542 1385627 2005 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cu-nanoparticles: a chemoselective catalyst for the aza-Michael reactions of N-alkyl- and N-arylpiperazines with acrylonitrile
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Cu-nanoparticles: a chemoselective catalyst for the aza-Michael reactions of N-alkyl- and N-arylpiperazines with acrylonitrile
چکیده انگلیسی

A novel method for effecting the aza-Michael reactions of N-alkyl- and N-arylpiperazines with acrylonitrile using Cu-nanoparticles is described. The method features the use of 10 mol % Cu (14-17 nm) nanoparticles under mild reaction conditions to afford the addition products in good to excellent yields. The Cu-nanoparticles selectively catalysed the aza-Michael reaction of N-alkyl- and N-arylpiperazines in the presence of aromatic amino or aliphatic hydroxy groups.

Cu-nanoparticles, 14-17 nm in size, efficiently catalyse the Michael-type reaction of N-alkyl- and N-arylpiperazines with acrylonitrile in high yield under mild reaction conditions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 46, Issue 31, 1 August 2005, Pages 5229-5232
نویسندگان
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