کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5434310 1509141 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel sensor made of Antimony Doped Tin Oxide-silica composite sol on a glassy carbon electrode modified by single-walled carbon nanotubes for detection of norepinephrine
ترجمه فارسی عنوان
حسگر جدید ساخته شده از پلیمر کامپوزیت اکسید تیتانیوم دوتایی تیتانیوم روی الکترود کربن شیشه ای اصلاح شده توسط نانولوله های کربنی تک محور برای تشخیص نوراپی نفرین
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
چکیده انگلیسی


- An imprinted electrochemical sensor was used for the detection of norepinephrine.
- The surface morphology of MIP film and MIP/SWNTs film was characterized by SEM.
- Using SWNTs to modify the electrodes can increase the electrochemical signals
- The sensor shows a low detection limit, wide linear range, and good reproducibility.

In this study, we designed a novel molecularly imprinted polymer (MIP), Antimony Doped Tin Oxide (ATO)-silica composite sol, which was made using a sol-gel method. Then a sensitive and selective imprinted electrochemical sensor was constructed with the ATO-silica composite sol on a glassy carbon electrode modified by single-walled carbon nanotubes (SWNTs). The introduction of SWNTs increased the sensitivity of the MIP sensor. The surface morphology of the MIP and MIP/SWNTs were characterized by scanning electron microscopy (SEM), and the optimal conditions for detection were determined. The oxidative peak current increased linearly with the concentration of norepinephrine in the range of 9.99 × 10− 8 M to 1.50 × 10− 5 M, as detected by cyclic voltammetry (CV), the detection limit was 3.33 × 10− 8 M (S/N = 3). In addition, the proposed electrochemical sensors were successfully applied to detect the norepinephrine concentration in human blood serum samples. The recoveries of the sensors varied from 99.67% to 104.17%, indicating that the sensor has potential for the determination of norepinephrine in clinical tests. Moreover, the imprinted electrochemical sensor was used to selectively detect norepinephrine. The analytical application was conducted successfully and yielded accurate and precise results.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 80, 1 November 2017, Pages 180-186
نویسندگان
, , , , , , ,