|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5434403||1398091||2017||10 صفحه PDF||سفارش دهید||دانلود کنید|
- A Zn-incorporated micro/nano-textured surface was prepared by anodization on pure Ti.
- The surface could continuously release Zn2Â + in a controlled manner.
- The surface could improve osteoblast functions when compared with Zn-free one.
It is acknowledged that ideal implant coatings should possess micro/nano-textured surface, have good interfacial bonding, and can release bioactive elements. In this study, we fabricated a Zn-incorporated micro/nano-textured surface by one-step high current anodization (HCA) in an aqueous solution with 10Â g/L of NaOH and different concentrations of Zn(NO3)2 (4, 7, and 12Â g/L). The control group of Zn-free was fabricated in the electrolyte of 7Â g/L Zn(NO3)2. Scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HR-TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and inductively coupled plasma mass spectroscopy (ICP-MS) were used to analyze the morphology, composition, microstructure, and Zn+ release kinetics of the micro/nano-textured coatings. The biological properties of the surface structure were evaluated by cytotoxicity assay, cell viability, cytoskeletal assembly and alkaline phosphatase activity. Our results show the micro/nano-textured surface is composed of TiO2 mesoporous arrays, into which the Zn is demonstrated to be incorporated in the form of ZnO. The Zn content in the surface and release level of Zn2Â + can be tailored through varying Zn(NO3)2 concentration in the electrolyte. In addition, the surface oxide layers show good interfacial bonding strength to the substrate. Compared with pure Ti and anodized Zn-free samples, the Zn-incorporated surface can upregulate osteoblast functions such as proliferation and alkaline phosphatase activity, which are assayed by MTT and ALP staining experiments, respectively. Collectively, this micro/nano-textured structure combined with high interfacial bonding strength and release of Zn2Â + render the material surface promising as orthopedic implant coatings.
Journal: Materials Science and Engineering: C - Volume 78, 1 September 2017, Pages 175-184