کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5434952 1509148 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Amplified nanostructure electrochemical sensor for simultaneous determination of captopril, acetaminophen, tyrosine and hydrochlorothiazide
ترجمه فارسی عنوان
سنسور الکتروشیمیایی نانوساختار تقویت شده جهت تعیین کاپتوپریل، استامینوفن، تیروزین و هیدروکلروتیازید همزمان
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
چکیده انگلیسی


- Fabrication of NiO/CNTs and new catechol derivative modified carbon paste electrode
- Good ability of proposed sensor for biological and pharmaceutical analysis
- Simultaneous determination captopril, acetaminophen, tyrosine and hydrochlorothiazide

A novel nanomaterial-based voltammetric sensor has been developed for use a highly sensitive tool for the simultaneous determination of captopril (CA), acetaminophen (AC), tyrosine (TY) and hydrochlorothiazide (HCTZ). The device is based on the application of NiO/CNTs and (2-(3,4-dihydroxyphenethyl)isoindoline-1,3-dione) (DPID) to modify carbon paste electrodes. The NiO/CNTs nanocomposite was synthesized through a direct chemical precipitation approach and was characterized with X-ray powder diffraction (XRD), and scanning electron microscopy (SEM). The NiO/CNTs/DPID/CPEs were found to facilitate the analysis of CA, AC, TY and HCTZ in the concentration ranges of 0.07-200.0, 0.8-550.0, 5.0-750.0 and 10.0-600.0 μM with the respective detection limits of 9.0 nM, 0.3 μM, 1.0 μM and 5.0 μM. The developed NiO/CNTs/DPID/CPEs were used for the determination of the mentioned analytes in pharmaceutical and biological real samples.

In this study a novel sensor based on NiO/CNTs and (2-(3,4-dihydroxyphenethyl)isoindoline-1,3-dione) (DPID) modified carbon paste electrode fabricated for simultaneous determination of captopril, acetaminophen, tyrosine and hydrochlorothiazide for the first time.93

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 73, 1 April 2017, Pages 472-477
نویسندگان
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