کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5495636 1529389 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Case reportCyberknife stereotactic radiosurgery and denosumab for giant cell tumour of the skull base: Case report
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم فیزیک هسته ای و انرژی بالا
پیش نمایش صفحه اول مقاله
Case reportCyberknife stereotactic radiosurgery and denosumab for giant cell tumour of the skull base: Case report
چکیده انگلیسی

Giant cell tumours (GCT) of the skull is a rare entity with only small number of cases reported in literature and optimal treatment is yet to be determined. These tumours have shown high recurrence rates after incomplete surgery, usually occurring during the first year. Even with new surgical techniques a complete resection in skull base tumours is not always possible without functional compromise. Therefore, adjuvant therapy is essential to enhance local control and quality of life. We report a rare case of a 34-year-old male with giant cell tumour (GCT) of the skull base involving the petrous bone, clivus and sphenoid body. The patient received Cyberknife stereotactic radiosurgery (CK SRS) and denosumab after surgery. This combined therapy allowed local control and tumour reduction with secondary neurological improvement during a 4-year follow up.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reports of Practical Oncology & Radiotherapy - Volume 22, Issue 6, November–December 2017, Pages 429-433
نویسندگان
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